Extra gene coding capacity of SARS-CoV-2 provides a virus engineering platform for in vitro and in vivo applications

Proceedings of the National Academy of Sciences, Volume 123, Issue 26, June 2026.
SignificanceGenetic engineering of viruses for heterologous gene expression provides diverse practical tools for research, prophylactic, and therapeutic applications. However, it often necessitates altering the natural genomic architecture of viruses, …
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