Proceedings of the National Academy of Sciences, Volume 122, Issue 21, May 2025.
SignificanceKoh et al. show that 15-hydroxyprostaglandin dehydrogenase (15-PGDH) is pathologically elevated in human and mouse Alzheimer’s disease (AD), traumatic brain injury (TBI), and aging, with 15-PGDH localized to myeloid cells of the blood–brain …
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